Welcome
The research
of the Biophotonics Laboratory, lead by Professor Changhuei
Yang is
focused on the development of novel tools that combine optics and
microfluidics to tackle diagnostic and measurement problems in biomedicine.
The major techniques that are under development in the laboratory include
Optofluidic Microscopy (OFM), Turbidity Suppression by Optical Phase
Conjugation (TSOPC), and Coherence Domain Probing System.
Optofluidic Microscopy is a unique way of scanning objects
without lenses, which can greatly reduce the size and the cost of
conventional microscopes. TSOPC probes the elastic optical scattering
in biological tissues, which has great potential in biomedical applications
such as tissue density heterogeneity determination, photodynamic
therapy, etc. Our research on Coherence Domain Probing System is
seeking to improve the current Optical Coherence Tomography (OCT)
technique for various clinical applications.
Some major research projects are outlined in the column on the right. For
more detailed information, please visit our research page. We are also pleased to include a link to the Optofluidics Webpage, which contains information on the collaborative efforts between Caltech, Harvard, Stanford and UCSD to further develop the field of optofluidics.
News
We are currently looking for new post-docs and graduate students. Interested candidates are welcome to contact Dr.Yang. The Biophotonics Lab, get directions, is located in the Moore Laboratory on the main Caltech campus. |
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Optofluidic Microscopy
Optofluidic Microscopy (OFM) is a new
compact and lensless microscopic imaging technique. OFM utilizes
microfluidic flow to deliver specimens across array(s) of micrometer-size
apertures defined on a metal-coated CMOS sensor to generate direct
projection images. Read more... |
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Turbidity
Suppression by Optical Phase Conjugation
Elastic optical scattering in biological
tissues typically dominates over absorption by an order of
magnitude or more. Elastic optical scattering is a deterministic
and time reversible process. By recording the phase and
amplitude of the propagating scattered light field and reproducing
a back-propagating optical phase conjugate (OPC) field, the
light should be able to retrace its trajectory through the
scattering medium and return the original input light field.
Read more... |
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Coherence
Domain Probing System
We are especially interested in the
development of the Optical Coherence Tomography system for
clinical applications. The research includes Paired Angle Rotation
Scanning OCT (PARS-OCT), Hand-Held Forward-Imaging Needle Endoscope,
etc. Read more... |
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