The Changhuei Yang Research Group [Publications]

Biophotonics Labotatory at Caltech

Peer-Reviewed Publications

2008

1. Zahid Yaqoob, Demetri Psaltis, Michael S. Feld & Changhuei Yang, 'Optical phase conjugation for turbidity suppression in biological samples', Nature Photonics Vol 2, 110 (2008). pdf http://www.nature.com/nphoton/journal/v2/n2/index.html

2. Shuo Han, Marinko V. Sarunic, Jigang Wu, Mark Humayun, and Changhuei Yang, 'Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection', Journal of Biomedical Optics Vol 13(2), 020505-1 (2008). pdf

3. Emily J. McDowell, Jian Ren, and Changhuei Yang, 'Fundamental sensitivity limit imposed by dark 1/f noise in the low optical signal detection regime', Optics Express Vol. 16, No. 10, 6822 (2008). pdf

2007

1. Jigang Wu, Zahid Yaqoob, Xin Heng, Lap Man Lee, Xiquan Cui, and Changhuei Yang. 'Full field phase imaging using a harmonically matched diffraction grating pair based homodyne quadrature interferometer,' Applied Physics Letters 90, 151123 (2007) pdf

2. Emily J. McDowell, Xiquan Cui, Zahid Yaqoob, and Changhuei Yang. 'A generalized noise variance analysis model and its application to the characterization of 1/f noise,' Optics Express, Vol. 15, No. 7, 3833 (2007) pdf

3. Emily J. McDowell, Marinko V. Sarunic, Zahid Yaqoob, and Changhuei Yang. ' SNR enhancement through phase dependent signal reconstruction algorithms for phas separated interferometric signals', Optics Express, Vol. 15, No. 16, 10103 (2007) pdf

4. Jeff Fingler, Dan Schwartz, Changhuei Yang, Scott E. Fraser. 'Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography'. Optics Express, Vol. 15, No. 20, 12653 (2007) pdf

5. Guoan Zheng, Lixin Ran, and Changhuei Yang, 'Electromagnetic equivalent model for phase conjugate mirror based on the utilization of left-handed material', Optics Express, Vol. 15, No. 21, 13877 (2007) pdf

6. Matthew Lew, Xiquan Cui, Xin Heng, and Changhuei Yang, 'Interference of a four-hole aperture for on-chip quantitative two-dimensional differential phase imaging', Optic Letters, Vol 32, No. 20, 2963 (2007) pdf

7. David T. Raphael, Changhuei Yang, Nancy Tresser, Jigang Wu,Yaoping Zhang,and Linda Rever, 'Images of Spinal Nerves and Adjacent Structures With Optical Coherence Tomography: Preliminary Animal Studies', The Journal of Pain, Vol 8, No 10, 767 (2007) pdf

8. Snow H. Tseng, Changhuei Yang, '2-D PSTD Simulation of optical phase conjugation for turbidity suppression', Optics Express, Vol. 15, No. 24, 16055 (2007) pdf

9. Xin Heng, Edward Hsiao, Demetri Psaltis, and Changhuei Yang, 'An optical tweezer actuated, nanoaperture-grid based Optofluidic Microscope implementation', Optics Express, Vol. 15, No. 25, 16367 (2007) pdf

10. Jigang Wu, Zahid Yaqoob, Xin Heng, Xiquan Cui, and Changhuei Yang, 'Harmonically matched grating-based full-field quantitative high-resolution phase microscope for observing dynamics of transparent biological samples', Optics Express, Vol 15, No. 26, 18141 (2007) pdf

2006

1. Jigang Wu, Michael Conry, Chunhui Gu, Fei Wang, Zahid Yaqoob, and Changhuei Yang. 'Paired-angle-rotation scanning optical coherence tomography forward-imaging probe,' Optics Letters, 31, 1265 (2006). pdf

2. Zahid Yaqoob, Jeff Fingler, Xin Heng, and Changhuei Yang. 'Homodyne en face optical coherence tomography,' Optics Letters 31, 1815 (2006). pdf

3. Demetri Psaltis, Steven Quake, and Changhuei Yang. 'Developing optofluidic technology through the fusion of microfluidics and optics,' Nature 442, 381 (2006). pdf

4. Xin Heng, David Erickson, Larry R. Baugh, Zahid Yaqoob, Paul W. Sternberg, Demetri Psaltis, and Changhuei Yang. 'Optofluidic microscopy: A Method for Implementing High Resolution Optical Microscope On A Chip,'Lab on a Chip 6, 1274 (2006). pdf

5. Xiquan Cui, Xin Heng, Jigang Wu, Zahid Yaqoob, Axel Scherer, Demetri Psaltis, and Changhuei Yang. 'Slanted Hole Array Beam Profiler (SHArP) - A high resolution on-chip beam profiler based on a linear aperture array,' Optics Letters 31, 3161 (2006). pdf

6. Zahid Yaqoob, Jigang Wu, Xiquan Cui, Xin Heng, and Changhuei Yang, 'Harmonically-related diffraction gratings-based interferometer for quadrature phase measurements,' Optics Express, Vol. 14, Issue 18, 8127 (2006) pdf

7. Zahid Yaqoob, Emily McDowell, Jigang Wu, Jeff Fingler, Xin Heng, Changuei Yang. 'Molecular contrast optical coherence tomography: A pump-probe scheme using indocyanine green as a contrast agent,' Journal of Biomedical Optics, Vol. 11, Issue 5, 1 (2006) pdf

8. Zahid Yaqoob, Jigang Wu, Emily J. McDowell, Xin Heng, Changhuei Yang. 'Methods and application areas of endoscopic optical coherence tomography,' Journal of Biomedical Optics, Vol. 11, Issue 6, 1 (2006) pdf

9. Xin Heng, Xiquan Cui, David W. Knapp, Jigang Wu, Zahid Yaqoob, Emily J. McDowell, Demetri Psaltis, and Changhuei Yang. 'Theoretical modeling and experimental characterization of the collection of light through a nanoaperture from a point source,' Optics Express, Vol. 14, No. 22, 10410 (2006) pdf

2005

1. Changhuei Yang. 'Molecular contrast optical coherence tomography: A review,' Photochemistry and Photobiology, 81:215 (2005). pdf

Book Chapter

1. Changhuei Yang, Xin Heng, Xiquan Cui and Demetri Psaltis, 'Optofluidic Microscope - Fitting a Microscope Onto a Sensor Chip' in 'CMOS Biotechnology' edited by Hankho Lee, Donhee Ham, Robert M. Westervelt, published by Springer, 2007

News Articles

2008

1. 'Optofluidics Emerges from the Laboratory', David Erickson, Cornell University, Changhuei Yang, California Institute of Technology, and Demetri Psaltis, Ecole Polytechnique Federale de Lausanne, Photonics Spectra, February 2008, p. 74-79. pdf

2. 'Gaining High Resolution with Nanoaperture Grid', Hank Hogan, Photonics Spectra, February 2008, p. 103. pdf

2007

1.Changhuei Yang and Demetri Psaltis, 'Building a Microscopic Microscope,' EAS ENG e n i o u s-Progress Report, pp.44-47, Spring 2007. pdf

2. Marinko Sarunic, Shuo Han, Jigang Wu, Zahid Yaqoob, Changhuei Yang, PARS-OCT endoscopy system, 'Ventilated Mouse Lung', Thorlabs. http://www.thorlabs.com/OCT/index.cfm?page=biomedical

3. 'Gradient Index Optical Microsystems Visualize Living Cells in Deep Tissue', Dr. Bernhard Messerschmidt, Grintech GmbH, Biophotonics International, September 2007, p. 36- 38. pdf

2006

1. 'Caltech Researchers Announce Invention of the Optofluidic Microscope,' Caltech Media Relations, September 5, 2006.http://pr.caltech.edu/media/Press_Releases/PR12888.html

2. Changhuei Yang, Xin Heng and Demetri Psaltis. 'Optofluidics reinvents the microscope,' Laser Focus World, Vol. 42, Issue 12, pp. 83-86, December 2006. pdf

3. Changhuei Yang and Demetri Psaltis. 'Optofluidics can create small, cheap biophotonic devices,' Laser Focus World, Vol. 42, Issue 6, pp. 85-88, July 2006. pdf

4. 'Optofluidic Microscope Enables Lensless Imaging of Microorganisms,' Biophotonics International, Volume 13, Number 10, October 2006. pdf

Pre-Group Publications

1. Kyungwon An, Changhuei Yang, Ramachandra R. Dasari, and Michael S. Feld, "Cavity ring-down technique and its application to measurement of ultraslow velocities", Optics Letters 20, pg. 1068 (1995).
2. Changhuei Yang, and Kyungwon An, "Quantum trajectory analysis of a thresholdlike transition in the microlaser", Physical Review A 55, pg. 4492 (1997).
3. Changhuei Yang, Kyungwon An, Lev T. Perelman, Ramachandra R. Dasari, and Michael S. Feld, "Spatial coherence of forward-scattered light in a turbid medium", Journal of the Optical Society of America A 16, pg. 866 (1999).
4. Changhuei Yang, Kyungwon An, Lev T. Perelman, Adam Wax, Ramachandra R. Dasari, and Michael S. Feld, "Feasibility of field-based light scattering spectroscopy", Journal of Biomedical Optics 5, pg. 138 (2000).
5. Changhuei Yang, Adam Wax, Irene Georgakoudi, Eugene B. Hanlon, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld, "Interferometric phase dispersion microscopy", Optics Letters 25, 1526 (2000). pdf
6. Changhuei Yang, Adam Wax, Michael S. Feld, "Measurement of anomalous phase velocity of ballistic light in a random medium using a novel interferometer", Optics Letters 26, 235 (2001). pdf
7. Changhuei Yang, Adam Wax, Ramachandra R. Dasari, Michael S. Feld, "Phase dispersion optical tomography", Optics Letters 26, 686 (2001). pdf
8. Changhuei Yang, Adam Wax, Mariah Hahn, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld, "The study of sub-wavelength and sub-Hertz cellular dynamics using a novel phase referenced interferometer", Optics Letters 26, 1271 (2001). pdf
9. Adam Wax, Changhuei Yang, Ramachandra R. Dasari, Michael S. Feld, "Measurement of angular distributions using low-coherence interferometry for lightscattering spectroscopy", Optics Letters 26, 322 (2001).
10. Adam Wax, Changhuei Yang, Ramachandra R. Dasari, Michael S. Feld, "Path-length-resolved dynamic light scattering: modeling the transition from single to diffusive scattering", Applied Optics 40, 4222 (2001).
11. Changhuei Yang, Adam Wax, Ramachandra R. Dasari, Michael S. Feld, "2<pi> ambiguity-free optical depth ranging with sub-nanometer precision using a novel phase-crossing low coherence interferometer", Optics Letters 27, 77 (2002). pdf
12. Adam Wax, Changhuei Yang, Vadim Backman, Maxim Kalashnikov, Ramachandra R. Dasari, and Michael S. Feld, "Determination of particle size using the angular distribution of backscattered light as measured with low-coherence interferometry", Journal of the Optical Society of America A 19, 737 (2002).
13. Adam Wax, Changhuei Yang, Vadim Backman, Kamran Badizadegan, Charles W. Boone, Ramachandra R. Dasari, Michael S. Feld, "Cellular organization and sub-structure measured using angle-resolved low coherence interferometry, " Biophysical Journal 82, 2256 (2002).
14. Changhuei Yang, Jerome Mertz, “Transmission confocal laser scanning microscopy with a virtual pinhole based on nonlinear detection”, Optics Letters 28, 224 (2003). pdf
15. Adam Wax, Changhuei Yang, Markus G. Müller, Ronald Nines, Charles W. Boone,
Vernon E. Steele, Gary D. Stoner, Ramachandra R. Dasari and Michael S. Feld, “In Situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry”, Cancer Research 63, 3556 (2003).
16. Adam Wax, Changhuei Yang, and Joseph Izatt, “Fourier-domain low coherence interferometry for light-scattering spectroscopy”, Optics Letters 28, 1230 (2003).
17. Michael Choma, Marinko Sarunic, Changhuei Yang, Joseph Izatt, “Sensitivity advantage of swept source and Fourier domain optical coherence tomography”, Optics Express 11, 2183 (2003). pdf
18. Michael Choma, Changhuei Yang, Joseph Izatt, “Instantaneous quadrature low-coherence interferometry with 3x3 fiber-optic couplers”, Optics Letters 28, 2162 (2003). pdf
19. Changhuei Yang, Siavash Yazdanfar, Joseph Izatt, “An amplified optical delay line based on the use of a linearly chirped fiber Bragg grating pair”, Optics Letters 29, 685 (2004). pdf
20. Changhuei Yang, Michael Choma, Laura Lamb, John Simon, Joseph Izatt, “Protein based molecular contrast OCT with phytochrome as the contrast agent”, Optics Letters 29, 1396 (2004). pdf
21. Changhuei Yang, Michael Choma, Brian Applegate, John Simon, Joseph Izatt, “Spectral triangulation molecular contrast OCT”, Optics Letters 29, 2016 (2004). pdf
22. Brian Applegate, Changhuei Yang, Andrew Rollins, Joseph Izatt, “Polarization resolved second harmonic generation optical coherence tomography in collagen”, Optics Letters 29, 2252 (2004).
23. Marinko V. Sarunic, Michael A. Choma, Changhuei Yang, Joseph A. Izatt, “Instantaneous complex spectral domain OCT using 3x3 fiber couplers”, Optics Express 13, 957 (2005).
24. Siavash Yazdanfar, Changhuei Yang, Marinko V. Sarunic, Joseph A. Izatt, “Frequency estimation precision in Doppler optical coherence tomography using the Cramer-Rao lower bound”, Optics Express 13, 410 (2005).
25. Andrew Ahn, Changhuei Yang, Adam Wax, Gabriel Popescu, Chris Fang-Yen, Kamran Badizadegan, Ramachandra Dasari, Michael Feld, “Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer”, Applied Optics 44, 1188-1190 (2005).
26. Brian E. Applegate, Changhuei Yang, Joseph A. Izatt, “Theoretical comparison of the sensitivity of molecular contrast optical coherence tomography techniques”, Optics Express 13, 8146-8163 (2005).
27. Michael. A. Choma, Audrey K. Ellerbee, Changhuei Yang, Joseph A. Izatt, “Spectral-domain phase microscopy”, Optics Letters 30, 1162-1164 (2005).

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