Biophotonics Laboratory
California Institute of Technology


Peer-Reviewed Publications
Book Chapter
News Articles
Pre-Group Publications


Peer-Reviewed Publications

84. X. Ou, R. Horstmeyer, G. Zheng and C. Yang; High numerical aperture Fourier ptychography: principle, implementation and characterization; Optics Express 2015, 23, pp. 3472-91. (pdf) (article link)

83. C. Han, J. Huangfu, L.L. Lai and C. Yang; A wide field-of-view scanning endoscope for whole anal canal imaging; Biomedical Optics Express 2015, 6, 607-614. (pdf) (article link)

82. M. Jang, H. Ruan, I.M. Vellekoop, B. Judkewitz, E. Chung and C. Yang; Relation between speckle decorrelation and optical phase conjugation (OPC)-based turbidity suppression through dynamic scattering media: a study on in vivo mouse skin; Biomedical Optics Express 2015, 6, 72-85. PMID: 25657876 [PubMed] PMCID: PMC4317115 (pdf) (article link)

81. *H. Ruan, *M. Jang, B. Judkewitz and C. Yang; Iterative Time-Reversed Ultrasonically Encoded Light Focusing in Backscattering Mode; Scientific Reports 2014, 4, Article number: 7156. PMID: 25412687; PMCID: PMC4239564; doi:10.1038/srep07156 (pdf)
(article link) *These authors contributed equally to this work.

80. E.H. Zhou, H. Ruan, C. Yang and B. Judkewitz; Focusing on moving targets through scattering samples; Optica 2014, 1, 227-32. PMID: 25621302 [PubMed] PMCID: PMC4301445; doi: 10.1364/OPTICA.1.000227 (pdf) (article link)

79. R. Horstmeyer, X. Ou, J. Chung, G. Zheng and C. Yang; Overlapped Fourier coding for optical aberration removal; Optics Express 2014, 22, 24062-80. PMID: 25321982; PMCID: PMC4247187; doi: 10.1364/OE.22.024062 (pdf) (article link)

78. J.H. Jung, C. Han, S.A. Lee, J. Kim and C. Yang; Microfluidic-integrated laser-controlled microactuators with on-chip microscopy imaging functionality; Royal Society of Chemistry: Lab on a Chip 2014, 14, 3781-89. PMID: 25099225; PMCID: PMC4153594; doi: 10.1039/C4LC00790E (pdf) (article link) (supplemental material 1) Also find suplemental video on article link.

77. S.A. Lee and C. Yang; A smartphone-based chip-scale microscope using ambient illumination; Royal Society of Chemistry: Lab on a Chip 2014, 14, 3056-3063. PMID: 24964209; PMCID: PMC4124038; doi: 10.1039/c4lc00523f (pdf) (article link) (supplemental video 1)
(supplemental video 2)

76. A. Williams, J. Chung, X. Ou, G. Zheng, S. Rawal, Z. Ao, R. Datar, C. Yang and R. Cote; Fourier ptychographic microscopy for filtration-based circulating tumor cell enumeration and analysis; Journal of Biomedical Optics (SPIE Digital Library) 2014, 19, 066007. PMID: 24949708 [PubMed - as supplied by publisher] doi: 10.1117/1.JBO.19.6.066007 (pdf) (article link)

75. J. Kim, J. Erath, A. Rodriguez and C. Yang; A high-efficiency microfluidic device for size-selective trapping and sorting; Lab on a Chip 2014, 14, 2480-90. PMID: 24850190; PMCID: PMC4073585; doi: 10.1039/C4LC00219A (pdf) (article link)

74. *M. Jang, *H. Ruan, E.H. Zhou, B. Judkewitz, and C. Yang; Method for auto-alignment of digital optical phase conjugation systems based on digital propagation; Optics Express 2014, 22, 14054-71. PMID: 24977504; PMCID: PMC4083057; doi: 10.1364/OE.22.014054 (pdf) (article link)
*These authors contributed equally to this work.

73. B. Judkewitz and C. Yang; Axial standing-wave illumination frequency-domain imaging (SWIF); Optics Express 2014, 22, 11001-10. PMID: 24921798; PMCID: PMC4083045; doi: 10.1364/OE.22.011001 (pdf) (article link)

72. J.L. Hollmann, R. Horstmeyer, C. Yang and C.A. DiMarzio; Diffusion model for ultrasound-modulated light; Journal of Biomedical Optics 2014, 19, 035005. PMID: 24638247 [PubMed - in process]; doi: 10.1117/1.JBO.19.3.035005 (pdf) (article link)

71. C. Han and C. Yang; Viral plaque analysis on a wide field-of-view, time-lapse, on-chip imaging platform; Analyst 2014, 139, 3727-34. PMID: 24611157; PMCID: PMC4077935; (pdf) (article link)

70. M. Jang, H. Ruan, B. Judkewitz and C. Yang; Model for estimating the penetration depth limit of the time-reversed ultrasonically encoded optical focusing technique; Optics Express 2014, 22, 5787- 5807. PMID: 24663917; PMCID: PMC4086332; (pdf) (article link)

69. S.A. Lee, J. Erath, G. Zheng, X. Ou, P. Willems, D. Eichinger, A. Rodriguez and C. Yang; Imaging and Identification of Waterborne Parasites Using a Chip-Scale Microscope; PLoS ONE 2014, 9, e89712. PMID: 24586978; PMCID: PMC3935895; doi:10.1371/journal.pone.0089712 (article link)

68. X. Ou, G. Zheng and C. Yang; Embedded pupil function recovery for Fourier ptychographic microscopy; Optics Express 2014, 22, 4960-72. PMID: 24663835; PMCID: PMC4086333; (pdf) (article link)

67. R. Horstmeyer and C. Yang; A phase space model of Fourier ptychographic microscopy; Optics Express 2014, 22, 338-58. PMID: 24514995; PMCID: PMC3926543; (pdf) (article link)

66. G. Zheng, X. Ou, and C. Yang; 0.5 gigapixel microscopy using a flatbed scanner; Biomedical Optics Express 2014, 5, 1-8. PMID: 24466471; PMCID: PMC3891323; doi:10.1364/BOE.5.000001 (pdf) (article link)

65. R. Horstmeyer, B. Judkewitz, I.M. Vellekoop, S. Assawaworrarit and C. Yang; Physical key-protected one-time pad; Nature Collections Scientific Reports 2013, 3, Article number 3543. PMID: 24345925; PMCID: PMC3866593; doi:10.1038/srep03543 (pdf) (article link)

64. *X. Ou, *R. Horstmeyer, C. Yang and G. Zheng; Quantitative phase imaging via Fourier ptychographic microscopy; Optics Letters 2013, 38, 4845-48. PMID: 24322147 [PubMed] PMCID: PMC4277232 (pdf) (article link) *These authors contributed equally to this work.

63. G. Zheng, R. Horstmeyer and C. Yang; Wide-field, high-resolution Fourier ptychographic microscopy; Nature Photonics 2013, 7, 739-45. PMID: 25243016; PMCID: PMC4169052; doi: 10.1038/nphoton.2013.187 (draft) (article link)

62. G. Zheng, X. Ou, R. Horstmeyer and C. Yang; Characterization of spatially varying aberrations for wide field-of-view microscopy; Optics Express 2013, 21, 15131-43. PMID: 23842300; PMCID: PMC3724395; (pdf) (article link)

61. S. Pang, C. Han, J. Erath, A. Rodriguez and C. Yang; Wide field-of-view Talbot grid-based microscopy for multicolor fluorescence imaging; Optics Express 2013, 21, 14555. PMID: 23787643; PMCID: PMC3726246; doi:10.1364/OE.21.014555 (pdf) (article link)

60. M. Jang, A. Sentenac and C. Yang; Optical phase conjugation (OPC)-assisted isotropic focusing; Optics Express 2013, 21, 8781-92. PMID: 23571967; PMCID: PMC3641024; (pdf) (article link)

59. S.A. Lee, X. Ou, J.E. Lee and C. Yang; Chip-scale fluorescence microscope based on a silo-filter complementary metal-oxide semiconductor image sensor; Optics Letters 2013, 38, 1817-19. PMID: 23722754; PMCID: PMC3740726; (pdf) (article link)

58. *B. Judkewitz, *Y.M. Wang, R. Horstmeyer, A. Mathy and C. Yang; Speckle-scale focusing in the diffusive regime with time-reversal of variance-encoded light (TROVE); Nature Photonics 2013, 7, 300-5. PMID: 23814605; PMCID: PMC3692396 doi: 10.1038/nphoton.2013.31 (draft) (article link) *These authors contributed equally to this work.

57. C. Han, S. Pang, D.V. Bower, P. Yiu and C. Yang; Wide Field-of-View On-Chip Talbot Fluorescence Microscopy for Longitudinal Cell Culture Monitoring from within the Incubator; Analytical Chemistry 2013, 85, 2356-60. PMID: 23350531; PMCID: PMC3587116; doi: 10.1021/ac303356v (pdf) (article link)

56. J.L. Hollmann, R. Horstmeyer, C. Yang and C.A. DiMarzio; Analysis and modeling of an ultrasound-modulated guidestar to increase the depth of focusing in a turbid medium; Journal of Biomedical Optics 2013, 18, 025004. PMID: 23400416 [PubMed - in process]
doi: 10.1117/1.JBO.18.2.025004 (pdf) (article link)

55. S. Pang, C. Han, M. Kato, P.W. Sternberg and C. Yang; Wide and scalable field-of-view Talbot-grid-based fluorescence microscopy; Optics Letters 2012, 37, 5018-20. PMID: 23202123; PMCID: PMC3718313; (pdf) (article link)

54. R. Horstmeyer, R.Y. Chen, B. Judkewitz and C. Yang; Markov speckle for efficient random bit generation; Optics Express 2012, 20, 26394-410. PMID: 23187494 [PubMed - in process] (pdf) (article link)

53. I.M. Vellekoop, M. Cui and C. Yang; Digital optical phase conjugation of fluorescence in turbid tissue; Applied Physics Letters 2012, 101, 1108. PMID: 22991478; PMCID: PMC3436909; doi: 10.1063/1.4745775 (pdf) (article link)

52. *Y.M. Wang, *B. Judkewitz, C.A. DiMarzio and C. Yang; Deep-tissue focal fluorescence imaging with digitally time-reversed ultrasound-encoded light; Nature Communications 2012, 3, Article number: 928. PMID: 22735456; PMCID: PMC3621452 doi: 10.1038/ncomms1925 (article link) *These authors contributed equally to this work.

51. S.A. Lee, G. Zheng, N. Mukherjee and C. Yang; On-chip continuous monitoring of motile microorganisms on an ePetri platform; Lab on a Chip 2012, 12, 2385-90. PMID: 22522781; PMCID: PMC3371133; doi: 10.1039/C2LC40090A (pdf)

50. J. Ren, X. Cui, L.M. Lee and C. Yang; Quantitative surface normal measurement by a wavefront camera; Optics Letters 2012, 37, 199-201. PMID: 22854466 [PubMed - in process] doi: 10.1364/OL.37.000199 (pdf)

49. S.A. Lee, R. Leitao, G. Zheng, S. Yang, A. Rodriguez and C. Yang; Color Capable Sub-Pixel Resolving Optofluidic Microscope and Its Application to Blood Cell Imaging for Malaria Diagnosis; PLoS ONE 2011, 6, e26127. PMID: 22022535; PMCID: PMC3191177 doi:10.1371/journal.pone.0026127 (pdf)

48. G. Zheng, C. Kolner and C. Yang; Microscopy refocusing and dark-field imaging by using a simple LED array; Optics Letters 2011, 36, 3987-89. PMID: 22002361 [PubMed - in process] L.36.003987 (pdf)

47. G. Zheng, S.A. Lee, Y. Antebi, M.B. Elowitz and C. Yang; The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM); Proceedings of the National Academy of Science 2011, 108, 16889-94. PMCID: PMC3193234; doi: 10.1073/pnas.11 10681108 (article link)

46. S. Pang, C. Han, L.M. Lee and C. Yang; Fluorescence microscopy imaging with a Fresnel zone plate array based optofluidic microscope; Lab on a Chip 2011, 11, 3698-702. PMID: 21935556; PMCID: PMC3710399; doi: 10.1039/c1lc20654k (pdf)

45. J. Wu, G. Zheng, Z. Li and C. Yang; Focal plane tuning in wide-field-of-view microscope with Talbot pattern illumination; Optics Letters 2011, 36, 2179-81. PMID: 21685959 [PubMed - indexed for MEDLINE] doi:10.1364/OL.36.002179 (pdf)

44. J. Ren, H.K. Gille, J. Wu and C. Yang; Ex vivo optical coherence tomography imaging of collector channels with a scanning endoscopic probe; Investigative Ophthalmology & Visual Science 2011, 52, 3921-25. PMID: 21357387 [PubMed - in process] doi: 10.1167/iovs.10-6744 (pdf)

43. G. Zheng, S.A. Lee, S. Yang and C. Yang; Sub-pixel resolving optofluidic microscope for on-chip cell imaging; Lab on a Chip 2010, 10, 3125-29. PMID: 20877904 [PubMed - indexed for MEDLINE] doi: 10.1039/c0lc00213e (pdf)

42. G. Zheng and C. Yang; Improving Weak-Signal Identification via Predetection Background Suppression by a Pixel-Level, Surface-Wave Enabled Dark-Field Aperture; Optics Letters 2010, 35, 2636-38. PMID: 20680083 [PubMed - in process] doi: 10.1364/OL.35.002636 (pdf)

41. X. Cui, J. Ren, G. Tearney and C. Yang; Wavefront Image Sensor Chip; Optics Express 2010, 18, 16685-701. PMID: 20721059; PMCID: PMC3408896 doi:10.1364/OE.18.016685 (pdf)

40. G. Zheng, Y.M. Wang and C. Yang; Pixel level optical-transfer-function design based on the surface-wave-interferometry aperture; Optics Express 2010, 18, 16499-506. PMID: 20721038; PMCID: PMC3408955 doi:10.1364/OE.18.016499 (pdf)

39. J. Wu, L.M. Lee and C. Yang; Focus grid generation by in-line holography; Optics Express 2010, 18, 14366-74. PMID: 20639921 [PubMed - in process] doi:10.1364/OE.18.014366 (pdf)

38. J. Wu, X. Cui, G. Zheng, Y.M. Wang, L.M. Lee and C. Yang; Wide field-of-view microscope based on holographic focus grid illumination; Optics Letters 2010, 35, 2188-90. PMID: 20596189 [PubMed - in process] doi:10.1364/OL.35.002188 (pdf)

37. G. Zheng, X. Cui and C. Yang; Surface-Wave-Enabled Darkfield Aperture for Background Suppression During Weak Signal Detection; Proceedings of the National Academy of Science 2010, 107, 9043-48. PMID: 20439760; PMCID: PMC2889114; doi:10.1073/pnas.0912563107 (pdf)

36. E.J. McDowell, M. Cui, I.M. Vellekoop, V. Senekerimyan, Z. Yaqoob and C. Yang; Turbidity suppression from the ballistic to the diffusive regime in biological tissues using optical phase conjugation; Journal of Biomedical Optics 2010, 15, 025004. PMID: 20459245; PMCID: PMC2874046 (pdf)

35. M. Cui and C. Yang; Implementation of a digital optical phase conjugation system and its application to study the robustness of turbidity suppression by phase conjugation; Optics Express 2010, 18, 3444-55. PMID: 20389354; PMCID: PMC3378352; doi:10.1364/OE.18.003444 (pdf)

34. S. Pang, X. Cui, J. DeModena, Y.M. Wang, P. Sternberg and C. Yang; Implementation of a color-capable optofluidic microscope on a RGB CMOS color sensor chip substrate; Lab on a Chip 2010, 10, 411-14. PMID: 20126679 [PubMed - in process] doi: 10.1039/b919004j (pdf)

33. M. Cui, E.J. McDowell and C. Yang; An in vivo study of turbidity suppression by optical phase conjugation (TSOPC) on rabbit ear; Optics Express 2010, 18, 25-30. PMID: 20173817; PMCID: PMC3369536; doi:10.1364/OE.18.000025 (pdf)

32. Y.M. Wang, G. Zheng, and C. Yang; Characterization of acceptance angles of small circular apertures; Optics Express 2009, 17, 23903-13. PMID: 20052101 [PubMed - indexed for MEDLINE] doi: 10.1364/OE.17.023903 (pdf)

31. J. Ren, J. Wu, E.J. McDowell and C. Yang; Manual-scanning optical coherence tomography probe based on position tracking; Optics Letters 2009, 34, 3400-02. Also published in Virtual Journal of Biological Physics Research 2009, 18, Instrumentation Development. PMID: 19881607 [PubMed - indexed for MEDLINE] doi:10.1364/OL.34.003400 (pdf)

30. M. Cui, E.J. McDowell and C. Yang; Observation of polarization-gate based reconstruction quality improvement during the process of turbidity suppression by optical phase conjugation; Applied Physics Letters 2009, 95, 123702-704. PMID: 19859580; PMCID: PMC2766401; doi:10.1063/1.3236836 (pdf)

29. L.M. Lee, X. Cui and C. Yang; The Application of on-chip Optofluidic Microscopy for Imaging Giardia lamblia Trophozoites and Cysts; Biomedical Microdevices 2009, 11, 951-58. PMID: 19365730; PMCID: PMC2888668; doi:10.1007/s10544-009-9312-x (pdf)

28. G. Zheng, X. Heng and C. Yang; A Phase Conjugate Mirror Inspired Approach for Building Cloaking Structures with Left-handed Materials; New Journal of Physics 2009, 11, 033010-25. PMID: 20126415; PMCID: PMC2814323 (pdf)

27. J. Wu, X. Cui, L.M. Lee and C. Yang; The application of Fresnel zone plate based projection in optofluidic microscopy; Optics Express 2008, 16, 15595-602. PMID: 18825198; PMCID: PMC2688452 (pdf)

26. X. Cui, M. Lew and C. Yang; Quantitative differential interference contrast microscopy based on structured-aperture interference; Applied Physics Letters 2008, 93, 091113-115. NIHMSID: 111214 (pdf)

25. X. Cui, L.M. Lee, X. Heng, W. Zhong, P.W. Sternberg, D. Psaltis and C. Yang; Lensless high-resolution on-chip optofluidic microscopes for Caenorhabditis elegans and cell imaging; Proceedings of the National Academy of Science 2008, 105, 10670-75. PMID: 18663227; PMCID: PMC2488383; (pdf)

24. Z. Yaqoob, D. Psaltis, M.S. Feld and C. Yang; Optical phase conjugation for turbidity suppression in biological samples; Nature Photonics 2008, 2, 110-115. PMID: 19492016; PMCID: PMC2688902 (article link)

23. S. Han, M.V. Sarunic, J. Wu, M. Humayun and C. Yang; Handheld forward-imaging needle endoscope for ophthalmic optical coherence tomography inspection; Journal of Biomedical Optics 2008, 13, 020505. PMID: 18465947 [PubMed - indexed for MEDLINE] (pdf)

22. E.J. McDowell, J. Ren and C. Yang; Fundamental sensitivity limit imposed by dark 1/f noise in the low optical signal detection regime; Optics Express 2008, 16, 6822-32. PMID: 18545385 [PubMed - indexed for MEDLINE] (pdf)

21. J. Wu, Z. Yaqoob, X. Heng, L.M. Lee, X. Cui and C. Yang; Full field phase imaging using a harmonically matched diffraction grating pair based homodyne quadrature interferometer; Applied Physics Letters 2007, 90, 151123-125. (pdf)

20. E.J. McDowell, X. Cui, Z. Yaqoob and C. Yang; A generalized noise variance analysis model and its application to the characterization of 1/f noise; Optics Express 2007, 15, 3833-48. PMID: 19532627 [PubMed - in process] (pdf)

19. E.J. McDowell, M.V. Sarunic, Z. Yaqoob and C. Yang; SNR enhancement through phase dependent signal reconstruction algorithms for phas separated interferometric signals; Optics Express 2007, 15, 10103-122. PMID: 19547360 [PubMed - in process] (pdf)

18. J. Fingler, D. Schwartz, C. Yang and S.E. Fraser; Mobility and transverse flow visualization using phase variance contrast with spectral domain optical coherence tomography; Optics Express 2007,15, 12636-653. PMID: 19550532 [PubMed - in process] (pdf)

17. G. Zheng, L. Ran and C. Yang; Electromagnetic equivalent model for phase conjugate mirror based on the utilization of left-handed material; Optics Express 2007, 15, 13877-885. PMID: 19550659 [PubMed - in process] (pdf)

16. M. Lew, X. Cui, X. Heng and C. Yang; Interference of a four-hole aperture for on-chip quantitative two-dimensional differential phase imaging; Optics Letters 2007, 32, 2963-65. PMID: 17938667; (pdf)

15. D.T. Raphael, C. Yang, N. Tresser, J. Wu, Y. Zhang and L. Rever; Images of Spinal Nerves and Adjacent Structures With Optical Coherence Tomography: Preliminary Animal Studies; The Journal of Pain 2007, 8, 767-73. PMID: 17586098 [PubMed - indexed for MEDLINE] (pdf)

14. S. H. Tseng and C. Yang; 2-D PSTD Simulation of optical phase conjugation for turbidity suppression; Optics Express 2007, 15, 16005-16. PMID: 19550887 [PubMed - in process] (pdf)

13. X. Heng, E. Hsiao, D. Psaltis and C. Yang; An optical tweezer actuated, nanoaperture-grid based Optofluidic Microscope implementation; Optics Express 2007, 15, 16367-75. PMID: 19550927 [PubMed - in process] (pdf)

12. J. Wu, Z. Yaqoob, X. Heng, X. Cui and C. Yang; Harmonically matched grating-based full-field quantitative high-resolution phase microscope for observing dynamics of transparent biological samples; Optics Express 2007, 15, 18141-55. PMID: 19551112 [PubMed - indexed for MEDLINE] (pdf)

11. J. Wu, M. Conry, C. Gu, F. Wang, Z. Yaqoob and C. Yang; Paired-angle-rotation scanning optical coherence tomography forward-imaging probe; Optics Letters 2007, 31, 1265-67. PMID: 16642080 [PubMed - indexed for MEDLINE] (pdf)

10. Z. Yaqoob, J. Fingler, X. Heng and C. Yang; Homodyne en face optical coherence tomography; Optics Letters 2006, 31, 1815-17. PMID: 16729080 [PubMed - indexed for MEDLINE] (pdf)

9. D. Psaltis, S. Quake and C. Yang; Developing optofluidic technology through the fusion of microfluidics and optics; Nature 2006, 442, 381-86. PMID: 16871205 [PubMed - indexed for MEDLINE] (pdf)

8. X. Heng, D. Erickson, L.R. Baugh, Z. Yaqoob, P.W. Sternberg, D. Psaltis and C. Yang; Optofluidic microscopy: A Method for Implementing High Resolution Optical Microscope On A Chip; Lab on a Chip 2006, 6, 1274-76. PMID: 17102839 [PubMed - indexed for MEDLINE] (pdf)

7. X. Cui, X. Heng, J. Wu, Z. Yaqoob, A. Scherer, D. Psaltis and C. Yang; Slanted Hole Array Beam Profiler (SHArP) - A high resolution on-chip beam profiler based on a linear aperture array; Optics Letters 2006, 31, 3161-63. PMID: 17041668 [PubMed] (pdf)

6. Z. Yaqoob, J. Wu, X. Cui, X. Heng and C. Yang; Harmonically-related diffraction gratings-based interferometer for quadrature phase measurements; Optics Express 2006, 14, 8127-37. PMID: 19529185 [PubMed - in process] (pdf)

5. Z. Yaqoob, E.J. McDowell, J. Wu, J. Fingler, X. Heng and C. Yang; Molecular contrast optical coherence tomography: A pump-probe scheme using indocyanine green as a contrast agent; Journal of Biomedical Optics 2006, 11, 054017. PMID: 17092166 [PubMed - indexed for MEDLINE] (pdf)

4. Z. Yaqoob, J. Wu, E.J. McDowell, X. Heng and C. Yang; Methods and application areas of endoscopic optical coherence tomography; Journal of Biomedical Optics 2006, 11, 063001. PMID: 17212523 [PubMed - indexed for MEDLINE] (pdf)

3. X. Heng, X. Cui, D.W. Knapp, J. Wu, Z. Yaqoob, E.J. McDowell, D. Psaltis and C. Yang; Characterization of light collection through a subwavelength aperture from a point source; Optics Express 2006 ,14, 10410-25. PMID: 19529440 [PubMed - indexed for MEDLINE] (pdf)

2. Z. Yaqoob, J. Wu and C. Yang; Spectral domain optical coherence tomography: a better OCT imaging strategy; BioTechniques 2005, 39, S6–S13. PMID 20158503 [PubMed – indexed for MEDLINE] (pdf)

1. C. Yang; Molecular contrast optical coherence tomography: A review; Photochemistry and Photobiology 2005, 81, 215-37. PMID: 15588122; PMCID: PMC1283114 (pdf)


2. Yeshaiahu Fainman, Luke Lee, Demetri Psaltis, and Changhuei Yang; Optofluidics: Fundamentals, Devices, and Applications (Biophotonics) published by McGraw-Hill, 2009 (ISBN-13: 978-0071601566)

1. Changhuei Yang, Xin Heng, Xiquan Cui and Demetri Psaltis, Ch. 10: Optofluidic Microscope - Fitting a Microscope Onto a Sensor Chip in CMOS Biotechnology edited by Hankho Lee, Donhee Ham, Robert M. Westervelt, published by Springer, 2007
(ISBN-13: 978-0387368368)


News Articles

36. Signal Processing Leads a Photographic and Imaging Revolution [Special Reports], by John Edwards; IEEE Signal Processing Magazine Vol 31 (3), 10-15, May 2014. (article link) (pdf)

35. The Computer Will See You Now, by Katherine Bourzac; Nature Vol 502, S92-S94, Oct 31, 2013. (article link) (pdf)

34. Turning a regular microscope into billion-pixel imaging system, by Elizabeth Armstrong Moore; CNET News, July 30, 2013. (article link) (pdf)

33. Pushing Microscopy Beyond Standard Limits, by Kimm Fesenmaier; Caltech Media Relations, July 2013. (article link)

32. Optofluidics 2013, by Ai-Qun Liu and Changhuei Yang; Editorial, Lab on a Chip Advance Article (2013) PMID: 23719899 [PubMed - as supplied by publisher] (pdf)

31. Themed issue: Optofluidics, by Ai-Qun Liu and Changhuei Yang; Editorial, Lab on a Chip 12(19): 3539–3539 (2012) PMID: 22895846 [PubMed] (pdf)

30. Acousto-optic imaging: Merging the best of two worlds, by G. Lerosey and M. Fink; Nature Photonics - News and Views, 7 (4), pp. 265–267. March 2013. (article link)

29. Surgery WITHOUT Cutting the Skin, by Dave Malkoff, KTLA Television News Reporter (@Malkoff & @KTLA). June 2012. (KTLA-TV Video Link)

28. Seeing Inside Tissue, by Marcus Woo. Caltech Media Relations, June 2012. (article link)

27. High-tech Petri dishes, by Erika Pastrana. Published online Nature Methods 8 (999), Nov 2011. doi:10.1038/nmeth.1786 (article link)

26. Feature of the Week 5/01/11: Caltech Researchers Develop an OCT Needle Probe for Investigating Open Angle Glaucoma, by Eric Swanson, Optical Coherence Tomography News (May 1, 2011). (article link)

25. Imaging: Phase sensor on a chip, by Oliver Graydon, Nature Photonics, Vol 4, pg 668, (2010) doi:10.1038/nphoton.2010.225 (article link)

24. Feature of the Week 2/7/10: Manual-Scanning Optical Coherence Tomography (OCT) Probe Based on Position Tracking, by Eric Swanson, Optical Coherence Tomography News (Feb 6 2010). (article link)

23. The most transparent research, by Melinda Wenner, Nature Medicine 15, 1106 - 1109 (2009), doi:10.1038/nm1009-1106. (pdf) (article link)

22. Microscopic marvels: Microscope for the masses, by Erika Check Hayden, Nature Vol 459, June 4, 2009, pp. 632-633. (pdf) (article link)

21. A Toymaker’s Lab, by Marcus Y. Woo. Engineering & Science, Spring 2009, pp. 22-27. (pdf)

20. The $10 Microscope, by Taylor Buley. 2009, LLC. (article link)

19. Optofluidics: Optofluidics Enhances Cytometry, by Changhuei Yang, David Erickson, and Demetri Psaltis, Bio Optics World, January 2009. (article link)

18. Microscope-On-a-Chip Is One Step Closer to the Tricorder, by Dave Bullock. WIRED, October 13, 2008. (article link)

17. Mini-Microscope Could Lead to Cell-Sorting Implants, by Alexis Madriga. WIRED, July 28, 2008. (article link)

16. New Micro-Microscope Is Portable And Cheap, National Public Radio Interview: Talk of the Nation, August 2008. (article link)

15. Microscope-on-a-Chip Is Small in Size, Big in Scope, by Shana Leonard. Medical Product Manufacturing News, October 2008. (pdf)

14. Caltech Bioengineers Develop "Microscope on a Chip," by Kathy Svitil. Caltech Media Relations, July 2008. (article link)

13. Bringing Microscopes Down to Size in Quest for More Compact Labs, by Henry Fountain. New York Times, July 2008. (article link)

12. Lensless On-Chip Microscope Inspired by "Floaters" in the Eye, by J. R. Minkel. Scientific American, July 2008. (article link)

11. Tiny $10 Microscope -- A high-resolution, lens-free microscope fits on a dime-size chip, by Katherine Bourzac. Technology Review, June 2008. (article link)

10. Optofluidics Emerges from the Laboratory, by David Erickson, Cornell University, Changhuei Yang, California Institute of Technology, and Demetri Psaltis, Ecole Polytechnique Federale de Lausanne. Photonics Spectra, February 2008, pp. 74-79. (pdf)

9. Gaining High Resolution with Nanoaperture Grid, by Hank Hogan. Photonics Spectra, February 2008, pp. 103. (pdf)

8. Getting in Deeper, by Hank Hogan. Biophotonics, July 2008, pp. 25. (pdf)

7. Building a Microscopic Microscope, by Changhuei Yang and Demetri Psaltis. EAS ENGenious - Progress Report, Spring 2007, pp.44-47. (pdf)

6. PARS-OCT Endoscopy System, by Marinko Sarunic, Shuo Han, Jigang Wu, Zahid Yaqoob, Changhuei Yang. Thorlabs

5. Gradient Index Optical Microsystems Visualize Living Cells in Deep Tissue, by Dr. Bernhard Messerschmidt, Grintech GmbH. Biophotonics International, September 2007, pp. 36-38. (pdf)

4. Caltech Researchers Announce Invention of the Optofluidic Microscope, Caltech Media Relations, September 5, 2006. (Press Release)

3. Optofluidics Reinvents the Microscope, by Changhuei Yang, Xin Heng and Demetri Psaltis. Laser Focus World Vol 42 (12), December 2006, pp. 83-86. (pdf)

2. Optofluidics can create small, cheap biophotonic devices, by Changhuei Yang and Demetri Psaltis. Laser Focus World Vol 42 (6), July 2006, pp. 85-88. (pdf)

1. Optofluidic Microscope Enables Lensless Imaging of Microorganisms, Biophotonics International Vol 13 (10), October 2006, pp. 24. (pdf)

Pre-Group Publications

27. Kyungwon An, Changhuei Yang, Ramachandra R. Dasari, and Michael S. Feld, Cavity ring-down technique and its application to measurement of ultraslow velocities, Optics Letters 20, 1068; 1995

26. Changhuei Yang, and Kyungwon An, Quantum trajectory analysis of a thresholdlike transition in the microlaser, Physical Review A 55, 4492; 1997

25. Changhuei Yang, Kyungwon An, Lev T. Perelman, Ramachandra R. Dasari, and Michael S. Feld, Spatial coherence of forward-scattered light in a turbid medium, Journal of the Optical Society of America A 16, 866;1999

24. Changhuei Yang, Kyungwon An, Lev T. Perelman, Adam Wax, Ramachandra R. Dasari, and Michael S. Feld, Feasibility of field-based light scattering spectroscopy, Journal of Biomedical Optics 5, 138; 2000

23. Changhuei Yang, Adam Wax, Irene Georgakoudi, Eugene B. Hanlon, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld, Interferometric phase dispersion microscopy, Optics Letters 25, 1526; 2000 (pdf)

22. Changhuei Yang, Adam Wax, Michael S. Feld, Measurement of anomalous phase velocity of ballistic light in a random medium using a novel interferometer, Optics Letters 26, 235; 2001 (pdf)

21. Changhuei Yang, Adam Wax, Ramachandra R. Dasari, Michael S. Feld, Phase dispersion optical tomography, Optics Letters 26, 686; 2001 (pdf)

20. Changhuei Yang, Adam Wax, Mariah Hahn, Kamran Badizadegan, Ramachandra R. Dasari, Michael S. Feld, The study of sub-wavelength and sub-Hertz cellular dynamics using a novel phase referenced interferometer, Optics Letters 26, 1271; 2001 (pdf)

19. Adam Wax, Changhuei Yang, Ramachandra R. Dasari, Michael S. Feld, Measurement of angular distributions using low-coherence interferometry for lightscattering spectroscopy, Optics Letters 26, 322; 2001

18. Adam Wax, Changhuei Yang, Ramachandra R. Dasari, Michael S. Feld, Path-length-resolved dynamic light scattering: modeling the transition from single to diffusive scattering, Applied Optics 40, 4222; 2001

17. Changhuei Yang, Adam Wax, Ramachandra R. Dasari, Michael S. Feld, 2<pi> ambiguity-free optical depth ranging with sub-nanometer precision using a novel phase-crossing low coherence interferometer, Optics Letters 27 (2), 77; 2002; PMID: 18007717 (pdf)

16. Adam Wax, Changhuei Yang, Vadim Backman, Maxim Kalashnikov, Ramachandra R. Dasari, and Michael S. Feld, Determination of particle size using the angular distribution of backscattered light as measured with low-coherence interferometry, Journal of the Optical Society of America A 19 (4), 737; 2002; PMID: 11934166 [PubMed - indexed for MEDLINE]

15. Adam Wax, Changhuei Yang, Vadim Backman, Kamran Badizadegan, Charles W. Boone, Ramachandra R. Dasari, Michael S. Feld, Cellular organization and sub-structure measured using angle-resolved low coherence interferometry, Biophysical Journal 82 (4), 2256; 2002; PMID: 11916880 [PubMed - indexed for MEDLINE]; PMCID: PMC1302018

14. Changhuei Yang, Jerome Mertz, Transmission confocal laser scanning microscopy with a virtual pinhole based on nonlinear detection, Optics Letters 28, 224; 2003 (pdf)

13. Adam Wax, Changhuei Yang, Markus G. Müller, Ronald Nines, Charles W. Boone, Vernon E. Steele, Gary D. Stoner, Ramachandra R. Dasari and Michael S. Feld, In Situ detection of neoplastic transformation and chemopreventive effects in rat esophagus epithelium using angle-resolved low-coherence interferometry, Cancer Research 63 (13), 3556; 2003; PMID: 12839941 [PubMed - indexed for MEDLINE]

12. Adam Wax, Changhuei Yang, and Joseph Izatt, Fourier-domain low coherence interferometry for light-scattering spectroscopy, Optics Letters 28 (14), 1230; 2003; PMID: 12885030 [PubMed - indexed for MEDLINE]

11. Michael Choma, Marinko Sarunic, Changhuei Yang, Joseph Izatt, Sensitivity advantage of swept source and Fourier domain optical coherence tomography, Optics Express 11 (18), 2183; 2003; PMID: 19466106 [PubMed - in process] (pdf)

10. Michael Choma, Changhuei Yang, Joseph Izatt, Instantaneous quadrature low-coherence interferometry with 3x3 fiber-optic couplers, Optics Letters 28 (22), 2162; 2003; PMID: 14649928 [PubMed - indexed for MEDLINE] (pdf)

9. Changhuei Yang, Siavash Yazdanfar, Joseph Izatt, Amplification of optical delay by use of matched linearly chirped fiber Bragg gratings, Optics Letters 29 (7), 685; 2004; PMID: 15072358 [PubMed - indexed for MEDLINE] (pdf)

8. Changhuei Yang, Michael Choma, Laura Lamb, John Simon, Joseph Izatt, Protein based molecular contrast OCT with phytochrome as the contrast agent, Optics Letters 29 (12), 1396; 2004; PMID: 15233447 [PubMed - indexed for MEDLINE] (pdf)

7. Changhuei Yang, Michael Choma, Brian Applegate, John Simon, Joseph Izatt, Spectral triangulation molecular contrast OCT with indocyanine green as the contrast agent, Optics Letters 29 (17), 2016; 2004; PMID: 15455765 [PubMed - indexed for MEDLINE]; PMCID: PMC1283115 (pdf)

6. Brian Applegate, Changhuei Yang, Andrew Rollins, Joseph Izatt, Polarization resolved second harmonic generation optical coherence tomography in collagen, Optics Letters 29 (19), 2252; 2004; PMID: 15524371 [PubMed - indexed for MEDLINE]

5. Marinko V. Sarunic, Michael A. Choma, Changhuei Yang, Joseph A. Izatt, Instantaneous complex spectral domain OCT using 3x3 fiber couplers, Optics Express 13 (3), 957-67; 2005; PMID: 19494959 [PubMed - in process]

4. Siavash Yazdanfar, Changhuei Yang, Marinko V. Sarunic, Joseph A. Izatt, Frequency estimation precision in Doppler optical coherence tomography using the Cramer-Rao lower bound, Optics Express 13 (2), 410-6; 2005;
PMID: 19488367 [PubMed - in process]

3. Andrew Ahn, Changhuei Yang, Adam Wax, Gabriel Popescu, Chris Fang-Yen, Kamran Badizadegan, Ramachandra Dasari, Michael Feld, Harmonic phase-dispersion microscope with a Mach-Zehnder interferometer, Applied Optics 44 (7), 1188-90; 2005; PMID: 15765698 [PubMed - indexed for MEDLINE]

2. Brian E. Applegate, Changhuei Yang, Joseph A. Izatt, Theoretical comparison of the sensitivity of molecular contrast optical coherence tomography techniques, Optics Express 13 (20), 8146-63; 2005; PMID: 19498844 [PubMed - in process]

1. Michael. A. Choma, Audrey K. Ellerbee, Changhuei Yang, Joseph A. Izatt, Spectral-domain phase microscopy, Optics Letters 30 (10), 1162-64; 2005; PMID: 15945141 [PubMed - indexed for MEDLINE]